There are a couple of interesting articles in this week’s print issue of The Economist, but they are both premium content on the web, so I’ve dug a bit deeper for you and will post on them separately. One article contrasts the global shortage of opiates for medical use with the efforts being made to stop Afghani farmers growing the opium poppy for the heroin trade. A crazy situation. One possible solution is licensing farmers to grow the crop under strict controls, but that is not without difficulties, especially in a place like Afghanistan. However, there is a possible scientific solution. It turns out that Tasmania, of all places, is an important opium poppy producer, and researchers at “Tasmanian Alkaloids recognised that there was a possibility of breeding a poppy variety in which the biosynthetic pathway stopped at thebaine instead of going on to produce morphine.” That would make it ok for therapeutic opiate production but useless for the illicit drug trade. You can read all about it here. There’s a paper on poppy transformation here and one on poppy genetic diversity here.
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