1) Today's been a hell of a day for plant #pangenomes.
In https://t.co/FSxNthxoG9 Walkowiak et al analyze up to 16 wheat cultivars to report on the global variation pool accessible to modern breeding pic.twitter.com/xPTtIvEZyC— BContrerasMoreira (@BrunoContrerasM) November 25, 2020
Indeed it was “a hell of a day” (somewhat re-ordered compared to the above tweet thread):
- Multiple wheat genomes reveal global variation in modern breeding. Genomes of 10 cultivars from around the world’s breeding programmes and a few other things added to that of Chinese Spring.
- A haplotype-led approach to increase the precision of wheat breeding. The above and fancy maths used to spot novel, agronomically significant haplotypes in landrace collections. Here’s a Twitter thread from one of the authors with his insights on why the work is important.
- The barley pan-genome reveals the hidden legacy of mutation breeding. Genomes of 20 really diverse barley lines, including a wild relative, used to (among other things) find novel variants in 300 genebank accessions.
- Assessing the regulatory potential of transposable elements using chromatin accessibility profiles of maize transposons. Some transposable elements affect gene expression.
- GreenPhylDB v5: a comparative pangenomic database for plant genomes. Pan-pangenomes, kinda.
LATER: Had completely forgotten I had used that title before :) It’s the zeitgeist for sure. And here’s a nice primer on pangenomes.
LATER STILL: Maybe it’s been a good year for something.
https://twitter.com/PacBio/status/1333429793115803648
Yes, there were lots of pangenomes in 2020: